Overall, 3.1% of children aged 8 to 17 had ever engaged in gambling activities. Binary logistic regression was used to examine the predictors of gambling participation while the qualitative data was analysed thematically. MethodsĪ cross-sectional convergent parallel mixed methodology was used to study 5024 children aged 8 to 17 in the three ecological zones of Ghana. This study examined the prevalence of gambling participation, predictors of gambling participation, and perceived harm of gambling on children. There are limited studies on child gambling in Ghana and other sub-Saharan African countries. Gambling is harmful and poses developmental implications for the youth, including children. However, young people, including children, are increasingly engaged in gambling across the country. Gambling is illegal for children in Ghana.